This is the sort of recurring pattern that one might expect to see in designed systems, but it is more surprising in stochastically evolved systems. It therefore suggests that operon regulation is best understood as the product of engineering rather than blind, unguided processes.
Recurring Design Logic in Attenuation Mechanisms Read More »
The design logic is the same. And yet, these two systems are not evolutionarily related to one another — as evidenced by the fact that the enzymes encoded by these two operons do not share sequence homology, indicating distinct evolutionary origins.
Recurring Design Logic in Operon Regulation Read More »
The headline that prompted me to read this paper claimed that the study “shows how bacteria evolved powered-up propellers.” But the paper does not do this at all. All it shows is another example of a flagellar protein that bears homology to a non-flagellar protein.
Fact Check: Has a Study Shown “How Bacteria Evolved Powered-Up Propellers”? Read More »
The origin of spliceosomal introns represents a significant challenge to an evolutionary account of their origins. While the hypothesis that group II introns from bacterial endosymbionts gave rise to eukaryotic introns is the prevailing explanation, it faces a series of substantial obstacles.
Evolutionary Obstacles to the Origin of Introns Read More »
There is a vast array of evidences, both internal and external, that reveal that the fourth gospel is composed by an individual who is extremely well informed, close up to the facts, and habitually scrupulous. This lays the foundation for multiple lines of argument for the truth of Christianity.
The Evidential Value of John’s Gospel to the Case for Christianity Read More »
Here, I want to draw attention to a review article by Levine and Holland, published in 2018, on “the impact of mitotic errors on cell proliferation and tumorigenesis.” Noting that “mitosis is a delicate event that must be executed with high fidelity to ensure genomic stability,” the paper underscores the critical nature of various aspects of the eukaryotic cell cycle machinery.
How Do Mitotic Errors Affect Cell Proliferation? Read More »
McClellan’s tone may suggest confidence, but his failure to engage seriously with the subject leaves the impression of bluster rather than substance.
Responding to Dan McClellan on the Resurrection Accounts Read More »
Any discussion of the evidence for the resurrection must first ascertain what the original apostolic witnesses claimed and whether those claims are best explained by the resurrection, or by some alternative hypothesis.
The Resurrection of Jesus: The Evidential Contribution of Luke-Acts Read More »
Recurring design logic across multiple unrelated systems is surprising in an evolutionary perspective, whereas on the hypothesis of design it is what might be reasonably predicted. Examples like this, therefore, suggest the existence of a master-architect behind biological systems — particularly when we find many different examples of design logic that are found recurrently throughout life.
Sporulation: Another Example of a Transcriptional Hierarchy Read More »
By an unguided process of tinkering, it seems quite implausible that the genes would be appropriately arranged along the chromosome in a manner that corresponds to the timing of their expression. Not only must the necessary genes be organized into a hierarchical transcriptional cascade to ensure proper timing and coordination of assembly, but the specific order of the genes along their respective operons is also significant.
Transcriptional Hierarchies Exhibit Recurring Design Logic and Challenge Evolution Read More »